Cat Scratch Fever, also known as Cat Scratch Disease (CSD), is caused by the bacterium Bartonella henselae. The primary mode of transmission is through the scratch or bite of an infected cat, particularly kittens. However, the bacteria can also be transmitted through a cat licking an open wound or through contact with the cat’s fur that has been contaminated with the bacterium. PCR Test helps to detect Cat Scratch Disease. It is the best and most accurate way to detect the disease.

General overview of how Cat Scratch Fever is caused.

Bartonella henselae Infection in Cats: Cats are the primary reservoir for Bartonella henselae. Many infected cats do not show any signs of illness, but they can carry the bacterium and shed it in their saliva, fur, and claws.

Transmission to Humans: Humans can contract the infection when bitten or scratched by an infected cat. The bacterium can enter the bloodstream through the site of the scratch or bite.

Symptoms and Disease Development: Cat scratch fever typically presents with symptoms such as fever, fatigue, headache, and swollen lymph nodes near the site of the scratch or bite. In some cases, the infection can lead to more severe complications, affecting the liver, spleen, or other organs.

It’s important to note that not all cats carry Bartonella henselae, and not all scratches or bites from infected cats will result in cat scratch fever. Additionally, good hygiene practices, such as washing hands after handling cats, can reduce the risk of infection. If someone experiences symptoms suggestive of cat scratch fever, they should seek medical attention for proper diagnosis and treatment.

Types of tests available:
Serological Tests: Enzyme Immunoassay (EIA) or Indirect Fluorescent Antibody (IFA): These tests detect antibodies produced by the immune system in response to Bartonella henselae infection.

Molecular Tests: Polymerase Chain Reaction (PCR): This method detects the genetic material of the bacterium in blood, tissue, or other body fluids. A Bartonella henselae PCR (Polymerase Chain Reaction) test is a molecular diagnostic test used to detect the genetic material of the bacterium Bartonella henselae. This bacterium is responsible for causing diseases such as cat scratch fever (CSD) in humans.

During the PCR test, a small sample of blood, tissue, or other body fluids is collected. The DNA in the sample is then amplified through multiple cycles of replication using the Polymerase Chain Reaction. If Bartonella henselae DNA is present in the sample, the test will produce a positive result.

PCR testing is particularly useful for detecting the presence of the bacterium in the early stages of infection or when the bacterial load is low. It provides a more direct and specific method compared to serological tests, which detect antibodies produced by the immune system.

Why test at AMMAGENOMICS?
AMMAGENOMICS Molecular Testing Laboratory is the pioneer lab to offer PCR-based test for the Cat Scratch Disease and gives accurate results in a quick turnaround time of five hours. We investigate the entire microbiome to find the root cause of the health issue and based on the test report we also provide free treatment counselling and guidance to get a complete cure.