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Mitochondrial Genetic Testing
Mitochondrial Genetic Testing refers to the analysis of the genetic material present in mitochondria, which are tiny structures within cells that play a crucial role in energy production. Unlike the nucleus of a cell, which contains most of the cell's genetic material (DNA), mitochondria have their own small circular DNA molecules. Mitochondria is the powerhouse of our body cells. If the mitochondria are strong and more in number, then we will have good energy. As we age, the mitochondria in our body decrease.
Mitochondrial Genetic Testing can serve various purposes, including:
Diagnosis of Mitochondrial Disorders:
- Mitochondrial disorders are a group of genetic conditions that can affect various body systems due to energy production problems. These disorders can result from mutations in either nuclear DNA or mitochondrial DNA (mtDNA). Testing can help diagnose the specific genetic cause of a patient's symptoms and guide appropriate medical management.
Assessment of Genetic Inheritance:
- Mitochondrial DNA is typically inherited from the mother. This means that if a mother has a mitochondrial DNA mutation, all of her children may inherit the mutation. Testing can be used to assess the likelihood of passing on mitochondrial disorders to future generations.
Identification of Heteroplasmy:
- Mitochondrial DNA mutations can sometimes exist in a mixture of normal and mutated forms within an individual, a condition known as heteroplasmy. The severity of symptoms in mitochondrial disorders can depend on the proportion of mutated mtDNA. Testing can help determine the level of heteroplasmy in a person's cells.
Research and Understanding:
Studying Mitochondrial DNA can provide insights into human evolution, population genetics, and migration patterns. It's also important for understanding the basic biology of mitochondria and how their genetic material affects cellular function.Forensic Analysis:
- Mitochondrial DNA can be more stable than nuclear DNA and is sometimes used in forensic analysis to identify individuals when nuclear DNA is degraded or unavailable.
Different methods for conducting mitochondrial genetic testing:
Sequencing:
Sequencing the entire mitochondrial genome can identify mutations associated with mitochondrial disorders and help determine heteroplasmy levels.Targeted Mutation Analysis:
If a specific mutation is suspected based on clinical symptoms, targeted testing can be performed to confirm the presence of that mutation.Heteroplasmy Assessment:
Techniques like quantitative PCR (Polymerase Chain Reaction) can help quantify the proportion of normal and mutant mitochondrial DNA.Next-Generation Sequencing:
Advanced sequencing technologies can quickly and efficiently sequence large numbers of mitochondrial genomes, aiding in research and diagnostics.
What We Do?
Mutations in mitochondrial DNA can lead to a group of disorders known as mitochondrial diseases. These disorders can affect various organs and systems in the body, often resulting in energy production deficits. Mitochondrial genetic testing is used to identify mutations in the mitochondrial DNA that may be responsible for these diseases. AMMAGENOMICS helps to diagnose individuals with suspected mitochondrial disorders and provides insights into potential treatments or management strategies.
Investigations
Blood Polyphenol Test
Blood Antioxidant Test
Blood Oxidant MDA Test
Gut Dysbiosis Test
Blood Bacteremia Test
Gut DNA Sequencing
Highlights of our Testing
Personalized Diagnosis
Lifestyle Suggestions
Dietary Suggestions
Mindfulness-based Interventions
Prognosis
Preventive Measures
Health Tips & Info
Mitochondrial Genetic Testing helps in the diagnosis of Mitochondrial Disorders which are genetic conditions that can affect various body systems due to energy production problems. We all know that Mitochondria is the powerhouse of our body cells. If the mitochondria are strong and in more numbers, then we will have good energy. As we age, the mitochondria in our body decrease. This testing can help diagnose the specific genetic cause of a patient's symptoms and guide appropriate medical management.
Mitochondrial Genetic Testing involves sequencing the mitochondrial DNA to identify any mutations or variations. This can be done through different techniques, such as Sanger sequencing, Next Generation Sequencing (NGS), or Whole Exome Sequencing. The specific method chosen depends on the purpose of the testing and the technology available.
Maternal Lineage Analysis traces an individual's maternal ancestry by examining specific regions of their mitochondrial DNA. Since mitochondrial DNA is passed down from mother to child without any recombination, it remains relatively unchanged over generations. By comparing the mitochondrial DNA sequences of different individuals, scientists can determine maternal relationships and construct family trees.
Mitochondrial Genetic Testing, also known as mitochondrial DNA (mtDNA) testing, is a type of genetic analysis that focuses on the DNA found within the mitochondria, the energy-producing structures within cells. Unlike nuclear DNA, which is inherited from both parents, mitochondrial DNA is solely inherited from the mother. This unique inheritance pattern makes mitochondrial genetic testing particularly useful for studying maternal lineage and certain types of genetic disorders that are caused by mutations in mitochondrial DNA.
Health Care Plans
Our doctors include highly qualified male and female practitioners who come from a range of backgrounds and bring with a diversity of skills and special interests. Our administration and support staff all have exceptional people skills and trained to assist you with all medical enquiries.
Health, Wellness and Specialized Tests
100% Customer Satisfaction Rate
Personalized Diagnostics & Treatment
Gut Dysbiosis Test
Polyphenol, Antioxidant & MDA Test
Blood Bacteremia Test
Preparing for a test help ensure it goes smoothly.
To reduce your wait time, complete the personal information on the form in advance for most routine tests.
Patient Centered Care
We work day and night to solve the problems of the patients who are seeking answers by giving Personalized Diagnostics and Treatment and helping them to move forward and have a positive impact on their life!
Quality Improvement
Our expert team typically processes over five hundred patients every month and gives accurate results in a quick turnaround time.
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Building Positive & Safe Patient Focused Culture.
With a belief that knowledge is power, we connect our patients directly with their results so they have valuable health information when they need it most, care about our people and are committed to excellence in the work we do for people to grow and strive for excellence.
Priya K. Chhalliyil
Our Founder
Health, Wellness and Specialized Tests
100% Customer Satisfaction Rate
Personalized Diagnostics & Treatment
At every step in the testing process, from collection to reporting, we provide caring, efficient, reliable and high-quality services. As a trusted partner supporting patients, healthcare providers and entire provincial healthcare systems, we are harnessing our medical expertise to build the best test offering while investing in technology.
We will work with you to develop individualized care plans, including the management of chronic diseases. If we cannot assist, we can provide referrals or advice about the type of practitioner you require to treat all enquiries sensitively.
Mitochondrial Genetic Testing can provide valuable information for diagnosing and managing mitochondrial disorders, understanding genetic inheritance patterns, and conducting scientific research.
Yes, of course, our treatment and suggestions work synergistically with all other medical systems of the world and other alternative therapies as well. Therefore do not stop other treatments you currently undergo. Discuss the results and therapy plan with your doctor and make suitable changes in your food and lifestyle with consent.
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