AMMAGENOMICS ACHIEVEMENTS & MILESTONES

AMMAGENOMICS offers mcfDNA-NGS — a culture-independent, pathogen-agnostic test for Fever of Unknown Origin and other diagnostically elusive infections. By sequencing circulating microbial cell-free DNA from blood, a single assay screens broadly across bacteria, fungi, and viruses, without the delay or organism bias of conventional culture. As a Laboratory Developed Test, results are reported for physician interpretation within the patient's full clinical context, complementing — not replacing — standard-of-care testing.

OORJV, our private food verification and quality rating initiative, issues its laboratory-backed certificates .This verified laboratory findings with their customers — extending AMMAGENOMICS' testing expertise into a dedicated consumer-facing certification programme.

AMMAGENOMICS offers PCR-based laboratory screening for selected DNA targets associated with rodents, reptiles such as lizards, and insects including cockroaches and houseflies. Results indicate whether the targeted DNA marker was detected or not detected under the test conditions. They do not establish when or how contamination occurred, confirm the safety of the entire food batch, or replace regulatory inspection, hygiene assessment, microbiological testing, or food-safety certification.

Our Chief Scientific Officer's book on the human microbiome translates complex gut science into plain language for patients, students, and clinicians. It covers the gut-brain axis, weight gain, inflammation, and oxidative stress. Just as a rainforest needs biodiversity to survive, your gut needs microbial diversity to stay healthy. Science that is understood is science that improves quality of life.

AMMAGENOMICS has introduced a molecular wellness coaching service to help individuals and families understand their personal biology through validated laboratory data. Our coaches translate complex test results — across gut health, hormonal balance, cellular energy, inflammation, and nutritional status — into clear, actionable insights that individuals can discuss with their own doctors and healthcare providers. This service is strictly educational and informational. It does not diagnose any condition, does not prescribe any treatment, and does not replace the advice of a licensed physician, specialist, or healthcare professional.

AMMAGENOMICS has launched a science-based counselling initiative to support cancer patients and their families in understanding the molecular landscape of their condition before, during, and after oncology interventions. AMMAGENOMICS does not prescribe, treat, or replace any medical intervention — we illuminate the molecular context that helps patients and doctors navigate the cancer journey with greater clarity and confidence.

AMMAGENOMICS has filed an international PCT (Patent Cooperation Treaty) patent application for a novel biomolecule separation technology, marking a defining moment in our journey from a Chennai-based laboratory to a globally recognised molecular diagnostics innovator.

AMMAGENOMICS is ISO 15189:2022 accredited for 43 laboratory tests across 22 biological matrices, comprising 28 oxidative stress, antioxidant, and polyphenol parameters and 15 molecular diagnostic assays. Our approved scope covers multi-biofluid testing, cell-free DNA/RNA profiling, microbiome analysis, mitochondrial and oxidative stress panels using validated real-time PCR platforms.

We are proud to announce that AMMAGENOMICS Food Testing Laboratory has been NABL accredited under ISO/IEC 17025:2017 (Certificate No. TC-12726) Valid 08 Dec 2025 to 07 Dec 2029. This accreditation confirms our technical competence, validated methods, and robust quality systems. Our accredited scope includes 148 discipline groups, covering food, water, and soil testing using real-time qPCR, 16S rRNA sequencing, ITS sequencing, and shotgun metagenomic analysis.

Developed different types of antioxidant tests on human biological fluids to know how the body manages oxidative stress and inflammation. Inflammation is like a small fire inside the body and Antioxidants act like fire extinguishers, helping to cool this internal fire. By understanding these tests, we can better guide nutritional and lifestyle choices to keep the body’s inner fire balanced and health maintained.

Brain Stress Highlighted the critical role of brain stress and cortisol regulation in preventing diseases linked to the gut–brain axis, microbiome balance, and inflammation. This milestone reflects our commitment to supporting emotional stress management across all age groups—from school students to professionals and retired individuals. This is different from the cortisol tests done in saliva.

Applied for multiple U.S. and international patents covering molecular testing parameters across diverse clinical and food sample matrices.

Achieved recognition by winning a prize in the LGC Raffle, Chennai. Participated in the QWAS Water Microbiology Proficiency Testing Scheme (lgcstandards.com/AXIO) and obtained satisfactory results in PCR-based water quality testing and pathogen detection in drinking water.

Developed Multi-Platform Total Antioxidant Capacity (TAC) tests System AMMAGENOMICS established a comprehensive TAC assay platform integrating DPPH, FRAP, ABTS, and Phosphomolybdenum assays to evaluate the redox potential of foods. These assays collectively measure the diverse antioxidant capacities of both hydrophilic and lipophilic compounds. While some methods assess the radical neutralization ability, others quantify the electron-transfer potential, offering a complete understanding of antioxidant strength and redox balance.

We’ve developed a novel diagnostic tool to detect mitochondrial dysfunction, now seen even in young adults and children. Mitochondria play a key role in energy, immunity, and overall cellular health and longevity. Early detection helps prevent damage and guides timely interventions. Dysfunction is linked to diseases like Parkinson’s, Alzheimer’s, cancer, arthritis, and infertility, premature ageing, muscular dystrophy etc

Cell-free DNA (cfDNA) testing is emerging as a powerful tool for early detection and preventive healthcare focused on aging and longevity. It reveals hidden inflammation and cellular damage that accelerate aging. By analyzing cfDNA, we can track molecular-level changes before symptoms appear. This insight enables timely lifestyle and health interventions to promote healthier aging.

AMMAGENOMICS has developed patent-pending, non-invasive urine-based diagnostic technologies avoiding blood tests for early detection of diseases like cancer, autoimmune disorders, and UTIs. Our approach eliminates the need for blood tests, making it ideal for all age groups including infants. It enables preventive care through molecular insights using urine biomarkers.

We are successfully developing PCR-based tests for detecting specific indigenous cow breeds. Based on customer needs, some of the breeds currently in the pipeline include Gir, Sahiwal, Red Sindhi, Tharparkar, Kankrej, Rathi, Ongole, Krishna Valley, Deoni, Hariana, Nagori, Kherigarh, Punganur, Vechur, Malnad Gidda, Hallikar, Amrit Mahal, Bargur, Kangayam, Umblachery, Lal Kandhari, Dangi, Gaolao, and Kasaragod Dwarf.

We have successfully collaborated with research institutes, contributing to novel experiment planning, innovative study designs, and unique interpretations, advancing scientific discovery. To further this mission, we have signed MOUs with reputed institutes to support scientific advancement.

We have developed innovative food tests that assess the health impact of foods in relation to prebiotics, probiotics, and postbiotics. These Lab Developed Tests (LDTs) provide valuable insights to guide informed food choices.

Several azoospermia and infertility informative tests with a very comprehensive view was developed to help infertility patients to attain natural or Assisted Reproductive Technology (ART) like IUD and IVF. Later when testicular Fine needle aspiration cytology (FNAC) test of the testicles was done normal sperms was noticed showing improvement in testicular function..

A proof of concept for a USA-based customer, exploring the effects of a breathing exercise on mitochondrial gene expression and function, gut microbiome, and blood inflammation, was successfully completed. The customer expressed high satisfaction with the exceptional service and the quality of data provided, all delivered on time in line with the agreed deadline.

A laboratory in USA successfully utilized the AMMAGENOMICS GUT Microbiome Extraction Kit to perform 16S sequencing. The study aimed to investigate whether the gut microbiome influences hormones and infertility issues. The lab is now preparing for a larger-scale study and publication, which is expected to reference the kit.

Digital PCR based high accurate Diagnostic Testing has been developed to detect even very low copy numbers for cancer markers and so very useful to see if chemotherapy or targeted therapy has removed all trace of cancer cells. We also use it to detect leaky gut causing bacteremia for allergies and skin diseases. Digital PCR or DDPCR is also used in food samples to detect even low level of adulteration in samples like ghee adulteration and other GMO analysis.

Elastase in stool or blood detection in stools are conventional ways of diagnosis of colon issues or for pancreatic insufficiency. We have developed the technology to extract RNA from stool and check for these markers for both leaky gut, and colon diseases.

Chemotherapy and radiation effectively kill cancer cells but often leave cancer stem cells (the "seeds" of cancer) untouched. This is akin to cutting down a tree without destroying its seeds. Over time, these seeds can spread and grow into new trees throughout the garden. Similarly, patients may initially celebrate the disappearance of their cancer, only to experience a relapse when the cancer reappears in new areas of the body because the cancer stem cells were not eradicated. AMMAGENOMICS has developed a comprehensive LDT test (LAb developed tests) to assess gut health, blood DNAemia, and inflammatory and cancer markers. These test helps in giving more information to physicains and patients to understand their health status.

Mitochondria is the Energy-battery of the cell. Most of the labs do exome sequencing for detecting mutations. We consider that looking at the functionality of mitochondria at the RNA level helps several mitochondrial related diseases like muscular dystrophy, ataxia, myopathy, neurological disorders, autism, cancer, diabetes, infertility, etc. MFusion: Indicates the level of mitochondrial fusion. MFission: Indicates the level of mitochondrial fission. AuTG: Indicates the level of mitochondrial autophagy. COX : Indicates the level of mitochondrial functionality. Therefore, testing mitochondrial health at the cellular level is vital for accurate diagnosis and effective treatment of diseases. This test helps in maintaining good health, preventing infertility, premature aging and useful for comparing chronological age with biological age.

In response to the growing demand for pinpointing the root causes of various diseases such as autoimmune disorders, cancer, allergies, and gut-related issues, we have developed highly precise DNAemia PCR tests. These tests accurately detect the presence of circulating bacterial DNA in the blood, which has been linked to conditions like diabetes, cardiovascular diseases, kidney failure, cancer, obesity, and gut dysbiosis, especially in older adults. Chronic low-grade inflammation from these conditions often remains undiagnosed, leading to degenerative diseases and causing sudden illness without prior warning. Our test has proven invaluable for many patients whose routine lab results appear normal but still experience health problems. It serves as an exceptionally accurate annual health checkup, aiding in disease prevention and early intervention.

AMMAGENOMICS has developed a test to detect if Basmati rice, renowned for its delightful fragrance, is adulterated with non-fragrant hybrids or ordinary rice varieties. This DNA PCR test offers a sensitive solution, capable of detecting even a single adulterated rice grain among 100 grains. This test ensures that customers can savor the authentic taste and aroma of traditional Basmati rice, assists exporters in obtaining certification, enables wholesalers, distributors, and farmers to demonstrate their commitment to quality and trustworthiness.

Alopecia areata, an autoimmune disorder, causes hair loss that does not respond to hair oils, supplements, DHT blockers, hormonal treatments, or even Platelet-rich Plasma Therapy (PRPT). Our new advanced tests identify the root causes of the problem, including gut health, probiotics, herbs, liver health, and scalp microbiome to detect dandruff-causing fungi and bacteria. These tests aid in the early detection and prevention of hair loss.

Children and adults are getting frequent ear infection and hearing loss (acute otitis media) and otosclerosis. The root cause of pus formation, pain and swelling is tested using Inflammation Markers RT-PCR Tests and Microbiota PCR Test. These tests developed by us are highly efficient tools for the early identification, prevention and treatment. These tests involve the detection of various pathogenic bacteria responsible for inflammation, enabling the assessment of its severity. The impact extends to individuals dealing with age-related concerns and those facing infertility issues.

We are honored to be the first laboratory accredited by both NABL and ISO for Polyphenols and Antioxidants testing in Foods. This not only boosts the market value of the products but also plays a role in promoting public health. Furthermore, there's a potential distinction as the inaugural accredited lab for A1 milk testing.

AMMAGENOMICS' Inflammation markers RT-PCR tests and Microbiota PCR Test for semen and prostate fluids have proven to be highly efficient tools for the early identification and prevention of Prostatitis. These tests involve the detection of various pathogenic bacteria responsible for inflammation, enabling the assessment of its severity. The impact extends to individuals dealing with age-related concerns and those facing infertility issues. Notably, these tests offer significant benefits to couples undergoing challenges in assisted reproductive treatments, such as IVF (In-Vitro Fertilization), IUI (Intrauterine Insemination), and ICSI (Intra Cytoplasmic Sperm Injection).

AMMAGENOMICS has created PCR-based tests for assessing gut microbiota associated with leaky gut, aiding in the identification of conditions like allergies, asthma, eosinophilia, hypersensitivity, immunity issues, skin diseases, eczema, seizures, epilepsy, psoriasis, food allergies, cancer, prolonged inflammation, and other autoimmune diseases.

The AMMAGENOMICS Microbiota PCR Test in Eye tear drops proves to be a highly effective tool for early detection and prevention of Cataract issues. This test can identify various pathogenic bacteria responsible for inflammation and retinal damage.

AMMAGENOMICS has innovated a single-step DNA/RNA kit, capable of generating top-tier DNA and RNA from challenging stool and soil samples. Our application for a patent for this groundbreaking kit is currently underway.

MA Omics, a division of AMMAGENOMICS LLP, has secured approval from the Food Safety and Standards Authority of India (FSSAI) to offer foods and food products with elevated medicinal value, a high polyphenol content, and low MDA levels.

AMMAGENOMICS has designed PCR and DNA Sequencing Tests specifically for assessing Soil Microbiota, offering valuable assistance to farmers and agricultural enterprises. These tests facilitate the evaluation of the proportion of beneficial and harmful bacteria within the soil microbiome. This information empowers farmers to enhance the presence of beneficial bacteria, ultimately influencing crop yields with a heightened polyphenol value.

AMMAGENOMICS has created PCR-based saliva microbiota tests aimed at preventing and addressing dental issues. Given that we consume 1.5 liters of saliva daily, detecting and addressing harmful bacteria is crucial to avoid various health concerns, including skin diseases, diabetes, heart diseases, persistent inflammation, epilepsy and other autoimmune conditions.

We've devised rapid tests to identify both prohibited and approved preservatives, particularly in elevated concentrations, found in various food categories such as milk, grains, spices, as well as Ayurvedic and Siddha medicines.

AMMAGENOMICS has created PCR-based tests for assessing gut microbiota associated with leaky gut, aiding in the identification of conditions like allergies, asthma, eosinophilia, hypersensitivity, immunity issues, skin diseases, eczema, seizures, epilepsy, psoriasis, food allergies, cancer, prolonged inflammation, and other autoimmune diseases.

AMMAGENOMICS developed RT-PCR Inflammatory Cytokine Marker Panel. This panel includes several cytokines and inflammatory interleukins and also virus-mediated interferon responses which help in the diagnosis of allergies, food allergies, cancer, long-term inflammation cancer and other autoimmune diseases.

Developed new tests to detect specific polyphenols like Quercetin, Ellagic Acids, and specific antioxidants like Ubiquinone in blood and other body fluids.

A Semen PCR Test helps to know if natural pregnancy will occur or need IUD / IVF methods. Microbiota Dysbiosis Test helps to know if Sperms are healthy. PCR Copy Number Test results give accurate details about Sperm Motility. RT-PCR RNA Genetic-Expression Test reveals inflammation that might prevent Sperm maturation.

We have developed a quicker and low-cost method for Microbiota Testing for those who need to know their Gut Microbiome. We can report this in 3 to 5 hours vs Sequencing which takes more than 1 to 2 months. Our customers are delighted with this testing strategy with our Patent Pending DNA Extraction Method.

Generally, sperm counting and motility are done for Semen Analysis. However, testing sperms at the genetic expression level is also needed to ensure the mitochondria copy numbers are sufficient for sperms to swim towards the ovum. Apart from this RNA Testing is needed to know if the sperm can fuse with an egg to guarantee success in a normal pregnancy or in ARTS like IVD and IUD. Click here to know the details.

Customers need fast testing reports on certified nutritional facts of foods. We have developed quick methods for Nutritional Analysis to comply with the government food license for Manufacturing, Selling and Exporting. We check for several contents in the foods with rapid turnaround time especially the new Nutrition Facts Label that is changing in several foods and drug governing administrations.

Our Patent Pending Nucleic Acid Extraction Kit including DNA and RNA shows high-quality results. Compared with other international branded kits in the market, our AMGCS Kit gives better yield, good CT value in PCR, Sequencing Data and reproducibility. The sequencing results comparing data from AMGCS Kit with the international branded kit can be seen on the Products page.

Currently, Hygienic Food Safety testing is very essential. However, we have developed some supplementary tests at the Molecular Level to improve food quality. These tests will help us to find food with high medicinal and protective values and also with low toxicity. Food is Medicine and it helps to prevent diabetes, cancer, cardiovascular diseases, dental issues and infertility problems.

These tests are not an alternative to existing diagnostic tests but add as supplementary tests to improve diagnostic efficiency for all diseases. These are good for diabetes, cancer, cardiovascular diseases, dental issues, and infertility problems, especially for improving the high success rate of IVF/IUD, etc.

We are the first pioneering Lab to successfully develop Polyphenols in saliva offering as a test for public. This test helps as an additional test for co-relating changes in diet for health and well-being. This also helps with dental health as well. This non-invasive diagnostic tool helps for quick and easy diagnostics with least discomfort to patients.

Food Pathogen DNA Testing for food poisoning was developed successfully.

Goat Meat (Mutton) Adulteration Test using PCR based DNA method to detect beef and buffalo was successful.

We are the first pioneering Lab to successfully develop Polyphenol Blood Test for co-relating to the effect of change in diet for health and well-being.

Honey Adulteration Test using PCR based DNA method and other chemical analysis was successfully developed.

AMMAGENOMICS did A1 Adulteration PCR Test in A2 Milk for a local milk supplier. We have successfully developed the Milk Adulteration Test.

AMMAGENOMICS successfully did DNA extraction of a challenging Cinnamon Tree Bark and did DNA Sequencing for meta-barcoding for a Plant Biotech Dept for a university in Coimbatore, Tamilnadu.

As a part of a Master's degree project in a famous dental college in Chennai, Tamilnadu, we performed DNA extraction and qPCR analysis of bacteria obtained from diabetic and healthy patients who had undergone root canal treatment. This success led us to take up Dental Microbiome projects.

Hiran, a Master's Degree intern student from Karaikal, Tamilnadu successfully did a complex project with us in Chemistry on Polyphenol Testing.

Developed RT-PCR COVID Detection Kit for AMMAGENOMICS and got approved by ICMR for COVID-19 Testing. We use our own kit for Covid and its variants' Testing.

Developed BioMTM (Molecular Transport Medium) used in collecting swab to do COVID testing for a Biotechnology company in Coimbatore, Tamil Nadu and got approved by ICMR for COVID-19 Testing.

Developed Magnetic Silica Based Technology for RNA Extraction as a kit for a Biotechnology company in Coimbatore, Tamil Nadu and got approved by ICMR for COVID-19 Testing.

Developed RNA Extraction Kit - Spin Column for a Biotechnology company in Coimbatore, Tamil Nadu and got approved by ICMR for COVID-19 Testing.

Developed Proof of Concept for a Biotechnology company in California, USA. PCR standardization for a Single Nucleotide change was successfully designed and tested.